DOGMA – A new PCOS theory

So I was doing more Google research on PCOS. The latest results I got from the doc showed everything was ‘normal’ and I was not insulin resistant. Or have high testosterone levels. Or biochemical hyperandrogenism. I have symptoms but no apparent biochemical reason for it. PLUS all the current recommended treatments for PCOS focus on the traditional PCOS phenotype – obese, IR and looking to conceive.

Okay, that’s my mini rant and I promise it does become relevant soon. So I’ve just finished moving house with the high stress levels and my diet/supplements going straight out the window I’m now on a 61 day cycle. I also got a mild case of thrush and started looking on the net for links to PCOS and stress in cases of thrush.

In my search I found a little bit of new information I hadn’t previously read, mostly from testimonials of very happy PCOS cysters. Women were telling the world about their treatment of candida and the subsequent (successful) treatment of their PCOS symptoms. The scientist in me is always skeptical of personal testimonials however in my research of PCOS it seems most of the evidence is in this form. Clinical trials are mostly small and focused mostly on the typical PCOS phenotypes and traditional treatment options (lifestyle, OCP’s, Metformin etc).

Then I came across a single paper that intrigued me. It’s clearly research in it’s early stage but does describe a new possible theory as to the development of PCOS known as Dysbiosis of Gut Microbiota (DOGMA). I also found an application for a clinical trial to take place in Australia that has been submitted in Nov last year. So maybe there’s something to this link between gut flora and PCOS.

Anyways, I needed to treat my thrush so I decided to make myself a guinea pig and follow the pathway I read about from Cara here http://optimalhealth.homestead.com/pcos.html. Three days ago I took my single dose of fluconazole (diflucan) and started on Ethical Nutrients Inner Health Plus.

And my first cycle in 61 days started this morning.

Looking good so far…….

So I’m going to continue with the probiotics for another month and see how regular my cycles become. If it turns out that I get back onto 28-30 day cycles believe me I’ll be shouting from the rooftops the success of probiotics. But still need to establish a pattern to my satisfaction. It certainly shouldn’t do any harm.

And nothing else has been working so far.

Keep you all posted 🙂

P.S  I know I’m late on my 60 day update so I’ll post an update on my PCOS journey once I find my scales and measuring tape in my new house. I’m sure they’re in there somewhere.

Reference:

Tremellen, K. & Karma, P. (2012). Dysbiosis of Gut Microbiota (DOGMA) – A novel theory for the development of Polycystic Ovarian Syndrome. Medical Hypotheses, Volume 79, issue 1 (July, 2012), p. 104-112.

Leave a comment